A Partial Listing of Dr. Whitelegge's Publications

Whitelegge JP, Gundersen C, Faull KF (1998) 'Electrospray-Ionization Mass Spectrometry of Intact Intrinsic Membrane Proteins.' Protein Science 7, 1423-1430.

Gundersen CB, Kohan S, Mastrogiacomo A, Whitelegge JP (1998) 'Intrinsic Membrane Association of Cysteine-string Proteins.' FEBS Lett. 436, 85-91.

Blanco DR, Whitelegge JP, Miller JN, Lovett MA (1999) Demonstration by mass spectrometry that purified native Treponema pallidum rare outer membrane protein 1 (Tromp1) has a cleaved signal peptide. Journal of Bacteriology 181, 5094-8.

Fluharty AL, Lombardo C, Louis A, Stevens RL, Whitelegge JP, Waring A, To T, Fluharty CB, and Faull KF (1999) Preparation of the cerebroside-sulfate activator (CSAct or Saposin B) from human urine. Molecular and Genetic Metabolism 68, 391-403.

Faull, K.F., Whitelegge, J.P., Higginson, J., Waring, A.J., To, T., Johnson, J., Krutchinsky, A.N., Standing, K.G., Waring, A.J., Stevens, R.L., Fluharty, C.B. and Fluharty, A.L. (1999) ‘Cerebroside sulfate activator protein (Saposin B):  Chromatographic and electrospray mass spectrometric properties.’ Journal of Mass Spectrometry 34, 1040-1054.

Whitelegge J.P., le Coutre J., Lee J.C., Engel C.K., Privé G.G., Faull K.F., and Kaback H.R. (1999) ‘Towards the Bilayer Proteome, Electrospray-Ionization Mass Spectrometry of Large Intact Transmembrane Proteins’ Proceedings of the National Acadamy of Sciences U.S.A. 96, 10695-10698.

Faull KF, Higginson J, Waring A, To T, Whitelegge JP, Stevens RL, Fluharty CB and Fluharty AL. (2000) 'The Hydrogen-deuterium exchange signature of porcine cerebroside sulfate activator protein.' Journal of Mass Spectrometry 35, 392-401.

Faull, K.F., Higginson, J., Waring, A.J., To, T., Stevens, R.L., Whitelegge, J.P., Fluharty, C.B. and Fluharty, A.L. (2000) Disulfide connectivity in cerebroside sulfate activator is not necessary for biological activity but is necessary for tertiary structure. Archives of Biochemistry and Biophysics 376, 266-74.

le Coutre J., Whitelegge J.P., Gross A., Turk E., Wright E.M., Kaback H.R. and Faull K.F. (2000) ‘Proteomics on Full-Length Membrane Proteins Using Mass Spectrometry’ Biochemistry 39, 4237-4242.

Turk E, Kim O, le Coutre J, Whitelegge JP, Eskandari S, Lam JT, Kreman M, Zampighi G, Faull KF, Wright EM. (2000) Molecular characterization of Vibrio parahaemolyticus vSGLT: a model for sodium-coupled sugar cotransporters. Journal of Biological Chemistry 275, 25711-25716.

Faull KF, Johnson J, Kim MJ, To T, Whitelegge JP, Stevens RL, Fluharty CB, Fluharty AL (2000) Structure of the asparagine-linked sugar chains of porcine kidney and human urine cerebroside sulfate activator protein.  Journal of Mass Spectrometry 35, 1416-24.

Whitelegge, J.P., Penn B, To T, Waring A, Sherman M, Stevens RL, Fluharty CB, Faull KF, Fluharty AL (2000) 'The effect of methionine oxidation upon the structure and function of the cerebroside-sulfate activator protein.' Protein Science 9, 1618-1630.

Fluharty AL Whitelegge, J.P., Penn B, To T, Waring A, Sherman M, Stevens RL, Fluharty CB, Faull KF (2001) A Comparative Lipid Binding Study on the Cerebroside Sulfate Activator (Saposin B).' Journal for Neuroscience Research 63, 82-9.

Suhr ST, Senut M-C, Whitelegge JP, Faull KF, Gage FH (2001) Identities of Sequestered Proteins in Aggregates from Cells with Induced Polyglutamine Expression. Journal of Cell Biology 153, 283-294.

Norris AJ; Whitelegge JP; Faull KF; Toyokuni T. (2001) Analysis of Enzyme Kinetics using Electrospray-Ionization Mass Spectrometry. Biochemistry 40, 3774-3779.

Zhang H, Whitelegge JP, Cramer WA. (2001) Ferredoxin: NADP⁺ oxidoreductase is a subunit of the chloroplast cytochrome b₆f complex. J Biol Chem 276, 38159-38165.

Schroda, M., Vallon, O., Whitelegge, J.P., Beck, C.F., Wollman, F.-A. (2001) Identification and Characterization of a Chloroplastic GrpE Homolog. The Plant Cell 13, 2823-2839.

Norris AJ; Whitelegge JP; Faull KF; Toyokuni T. (2001) Kinetic Characterization of Enzyme Inhibitors Using Electrospray-Ionization Mass Spectrometry Coupled with Multiple Reaction Monitoring. Analytical Chemistry 73, 6024-6029.

Behnam K, Murray SS, Whitelegge JP and Brochmann E. (2002) Identification of the molecular chaparone alpha B-crystallin in demineralized bone powder and osteoblast-like cells.  Journal of Orthopaedic Research 20, 1190-1196.

Ahn VE, Faull KF, Whitelegge, JP, Higginson J, Fluharty AL, Prive GG (2003) Expression, purification, crystallization and preliminary X-ray analysis of recombinant human Saposin B. Protein Expression and Purification 27, 186-93.

Gómez SM, Nishio JN, Faull KF, Whitelegge JP. (2002) The chloroplast grana proteome defined by intact mass measurements from LC-MS. Molecular and Cellular Proteomics 1, 45-59.

Whitelegge JP, Gómez SM, Aguilera R, Roberson RW, Vermaas WF, Crother TR, Champion CI, Nally JE, Blanco DR, Lovett MA, Miller JN, Faull KF. (2002) Identification of Proteins and Intact Mass Measurements in Proteomics. Applied Genomics and Proteomics 1, 85-94.

Whitelegge JP, R. Aguilera, H. Zhang, R. Taylor, W.A Cramer (2002) Full subunit coverage liquid chromatography electrospray-ionization mass spectrometry (LCMS+) of an Oligomeric Membrane Protein: Cytochrome b₆f Complex from Spinach and the Cyanobacterium, M. laminosus. (2002). Molecular and Cellular Proteomics 1, 816-827.

Ahn VE, Faull KF, Whitelegge, JP, Fluharty AL, Prive GG (2003) Crystal structure of Saposin B. reveals a dimeric shell for lipid binding. Proceedings of the National Academy of Sciences U.S.A. 100, 38-43.

Weinglass A, Whitelegge JP, Hu Y, Verner G, Faull KF, Kaback HR (2003) Elucidation of substrate binding interactions in a membrane transport protein by mass spectrometry.  EMBO J. 22, 1467 - 1477.

Kinzie SD, Thevis M, Ngo K, Whitelegge J, Loo JA, Abu-Omar MM. (2003) Posttranslational Hydroxylation of Human Phenylalanine Hydroxylase Is a Novel Example of Enzyme Self-Repair within the Second Coordination Sphere of Catalytic Iron. J. Am. Chem. Soc. 125, 4710-1.

Slaughter N, Laux I, Tu X, Whitelegge J, Zhu X, Effros R, Bickel P, Nel A. (2003) The flotillins are integral membrane proteins in lipid rafts that contain TCR-associated signaling components: implications for T-cell activation. Clin Immunol. 108(2): 138-51.

Gómez SM, Bil' KY, Aguilera R, Nishio JN, Faull KF, Whitelegge JP. (2003) Transit peptide cleavage sites of integral thylakoid membrane proteins. Mol Cell Proteomics 2 (10), 1068-85.

Whitelegge JP, Ahn V., Norris AJ, Sung H, Johnson J, Waring A, Stevens RL, Fluharty CB, Prive G, Faull KF, Fluharty AL. (2003) Characterization of a recombinant molecule covalently indistinguishable from human Cerebroside-Sulfate Activator Protein (CSAct or Saposin B). Cell. Mol. Biol. 49 (5), 799-807.

Bortz E, Whitelegge JP, Jia Q, Zhou ZH, Stewart JP, Wu TT, Sun R. (2003) Identification of Proteins Associated with Murine Gammaherpesvirus 68 Virions. J Virol. 77(24), 13425-13432.

Faham S, Yang D, Bare E, Yohannan S, Whitelegge JP, Bowie JU. (2004) Side-chain Contributions to Membrane Protein Structure and Stability. J Mol Biol. 335(1), 297-305.

Whitelegge JP (2003) Thylakoid membrane proteomics. Photosynthesis Research 78, 265-277.

Norris AJ, Whitelegge JP, Strouse MJ, Faull KF, Toyokuni T. (2004) Inhibition kinetics of carba- and C-fucosyl analogues of GDP-fucose against fucosyltransferase V: implication for the reaction mechanism. Bioorg Med Chem Lett. 14(3):571-3.

Yohannan S, Faham S, Yang D, Whitelegge JP, Bowie JU (2004) The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors. Proc Natl Acad Sci U S A, 101(4):959-63.

Tu, X, Huang, A., Bae, D., Slaughter, N., Whitelegge, J.P., Crother, T., Nel, A. Use of Proteomics to characterize TCR-Associated Signaling Complexes In Lipid Rafts from a T-cell line. Journal of Proteome Research, 3(3):445-54.

Puppione, D.L., Fischer, W.H., Park, M., Whitelegge, J.P., Schumaker, V.N., Golfeiz, S., MacDonald, M.H. (2004) Sequence of horse (Equus caballus) apoA-II. Another example of a dimer forming apolipoprotein. Comparative Biochemistry and Physiology B, 138, 213-220.

Whitelegge, J.P., Katz, J., Pihakari, K., Hale, R., Aguilera, R.,  Gómez, S.M., Faull, K.F., Vavilin, D, Vermaas, W. (2004) Subtle modifcation of isotope ratio proteomics (SMIRP); a new strategy for expression proteomics. Phytochemistry, 65(11), 1507-1515.

Crother, T., Nally, J., Blanco, D., Champion, C., Whitelegge, J.P., Lovett, T.C. (2004) Temporal Analysis of the Antigenic Composition of Borrelia burgdorferi during Infection in Rabbit Skin. Infection and Immunity 72(9), 5063-72.

Yohannan, S., Duan Yang, D., Faham, S., Boulting, G., Whitelegge, J.P., Bowie, J.U. Proline substitutions are not easily accommodated in a membrane protein. J. Mol. Biol. 341, 1-6.

Chun, H.H., Cary, R.B., Lansigan, F., Whitelegge, J.P., Rawlings, D.J., Gatti, R.A. (2004) ATM Protein Purified From Vaccinia Virus Expression. Biochem. Biophys. Res. Commun. 322, 74-81.

Weinglass, A., Whitelegge, J.P., Faull, K.F., Kaback, H.R. Monitoring conformational re-arrangements in the substrate-binding site of a membrane transport protein by mass spectrometry. J. Biol. Chem., 279(40), 41858-65.

Nally, J.E., Whitelegge, J.P., Aguilera, R., Pereira, M.M., Blanco, D.R., Lovett, M.A. (2005) Purification and proteomic analysis of outer membrane vesicles from a clinical isolate of Leptospira interrogans serovar Copenhageni. Proteomics 5(1), 144-52.

Weinglass, A.B., Soskine, M., Vazquez-Ibar, J.L., Whitelegge, J.P., Faull, K.F., Kaback, H.R., Schuldiner, S. (2005) Exploring the role of a unique carboxyl residue in substrate binding to EmrE by mass spectrometry. J. Biol. Chem. 280(9), 7487-92.

Barwe, S.P., Anilkumar, G., Moon, S.Y., Zheng, Y., Whitelegge, J.P., Rajasekaran, S.A., Rajasekaran, A.K. (2005) Novel Role for Na,K-ATPase in Phosphatidylinositol 3-Kinase Signaling and Suppression of Cell Motility. Mol. Biol. Cell 16(3), 1082-94.

Liu, C., Willmund, F., Whitelegge, J.P., Hawat, S., Knapp, B., Lodha, M., Schroda, M. (2005) J-Domain Protein CDJ2 and HSP70B Are a Plastidic Chaperone Pair That Interacts with Vesicle-Inducing Protein in Plastids. Mol. Biol. Cell 16(3), 1165-77.

Whitelegge, J.P. (2005) Mass spectrometry for high throughput quantitative proteomics in plant research: lessons from thylakoid membranes. Plant Physiol. Biochem. 42(12), 919-27.

Puppione, D.L., Whitelegge, J.P., Yam, L.M., Schumaker, V.N. (2005) Mass spectral analysis of pig (Sus scrofa) apo HDL: identification of pig apoA-II, a dimeric apolipoprotein. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 141(1), 89-94.

Blanco, D.R., Champion, C.I., Dooley, A., Cox, D.L., Whitelegge, J.P., Faull, K., Lovett, M.A. (2005) A monoclonal antibody that conveys in vitro killing and partial protection in experimental syphilis binds a phosphorylcholine surface epitope of Treponema pallidum. Infect Immun. 73, 3083-95.

Lu, M., Zhang, L., Maul, R.S., Sartippour, M.R., Norris, A., Whitelegge, J., Rao, J.Y., Brooks, M.N. (2005) The Novel Gene EG-1 Stimulates Cellular Proliferation. Cancer Res. 65 (14), 6159-66.

Whitelegge, J.P. (2005) Tandem Mass Spectrometry of Integral Membrane Proteins for Top-Down Proteomics. Trends in Analytical Chemistry 24 (7), 576-582.

Berhane, B.T., Zong, C., Liem, D.A., Huang, A., Le, S., Edmondson, R.D., Jones, R.C., Qiao, X., Whitelegge, J.P., Ping, P., Vondriska, T.M. (2005) Cardiovascular-related proteins identified in human plasma by the HUPO Plasma Proteome Project Pilot Phase. Proteomics 5 (13), 3520-3530.

Kozak, N.A., Mattoo, S., Foreman-Wykert, A.K., Whitelegge, J.P., Miller, J.F. (2005) Interactions between Partner Switcher Orthologs BtrW and BtrV Regulate Type III Secretion in Bordetella. J Bacteriol. 187(16), 5665-76.

Norris, A.J., Whitelegge, J.P., Yaghoubian, A., Alattia, J.R., Prive, G.G., Toyokuni, T., Sun, H., Brooks, M.N., Panza, L., Matto, P., Compostella, F., Remmel, N., Klingenstein, R., Sandhoff, K., Fluharty, C., Fluharty, A., Faull, K.F. (2005) A novel mass spectrometric assay for the cerebroside sulfate activator protein (saposin B) and arylsulfatase A. J Lipid Res. 46, 2254-64.

Gomes AV, Zong C, Edmondson RD, Berhane BT, Wang GW, LE S, Young G, Zhang J, Vondriska TM, Whitelegge JP, Jones RC, Joshua IG, Thyparambil S, Pantaleon D, Qiao J, Loo J, Ping P. (2005) The Murine Cardiac 26S Proteasome: An Organelle Awaiting Exploration. Ann N Y Acad Sci. 1047, 197-207.

Porras-Yakushi TR, Whitelegge JP, Miranda TB, Clarke S. (2005) A novel SET-domain methyltransferase modifies ribosomal protein Rpl23ab in yeast. J. Biol Chem. 280, 34590-8.

Puppione DL, Whitelegge JP, Yam LM, Bassilian S, Schumaker VN, Macdonald MH. (2005) Mass spectral analysis of domestic and wild equine apoA-I and A-II: Detection of unique dimeric forms of apoA-II. Comp Biochem Physiol B Biochem Mol Biol. 142, 369-73.

Kozak KR, Su F, Whitelegge JP, Faull K, Reddy S, Farias-Eisner R. (2005) Characterization of serum biomarkers for detection of early stage ovarian cancer. Proteomics 5(17), 4589-96.

Qiao F, Harada B, Song H, Whitelegge J, Courey AJ, Bowie JU. (2006) Mae inhibits Pointed-P2 transcriptional activity by blocking its MAPK docking site. EMBO J. 25(1), 70-9.

Bindschedler LV, Whitelegge JP, Millar DJ, Bolwell GP. (2006) A two component chitin-binding protein from French bean -- association of a proline-rich protein with a cysteine-rich polypeptide.FEBS Lett. 580(6), 1541-6.

Whitelegge JP, Laganowsky A, Nishio J, Souda P, Zhang H, Cramer WA. (2006) Sequencing covalent modifications of membrane proteins. J Exp Bot. 57(7), 1515-22.

Shaw, B.F., Durazo, A., Nersissian, A.M., Whitelegge, J.P., Faull, K.F., Valentine, J.S. (2006) Local unfolding in a destabilized, pathogenic variant of superoxide dismutase 1 observed with H/D exchange and mass spectrometry. J Biol Chem. 281(26):18167-76.

Puppione DL, Yam LM, Bassilian S, Souda P, Castellani LW, Schumaker VN, Whitelegge JP. (2006) Mass spectral analysis of the apolipoproteins on mouse high density lipoproteins. Detection of post-translational modifications.Biochim Biophys Acta. 1764(8):1363-71.

Ding Q, Vaynman S, Souda P, Whitelegge JP, Gomez-Pinilla F. (2006) Exercise affects energy metabolism and neural plasticity-related proteins in the hippocampus as revealed by proteomic analysis. Eur J Neurosci. 24(5):1265-76.

Porras-Yakushi TR, Whitelegge JP, Clarke S. (2006) A novel set-domain methyltransferase in yeast: Rkm2-dependent trimethylation of ribosomal protein L12ab at lysine 10. J Biol Chem. 281(47):35835-45.

Nally JE, Whitelegge JP, Bassilian S, Blanco DR, Lovett MA. (2006) Characterization of the outer membrane proteome of Leptospira interrogans expressed during acute lethal infection. Infect Immun. 75(2):766-73.

Kawaguchi, R., Yu, J., Honda, J., Hu, J., Whitelegge, J.P., Ping, P., Wiita, P., Bok, D., Sun, H. (2007) A Membrane Receptor for Retinol Binding Protein Mediates Cellular Uptake of Vitamin A. Science, 315(5813):820-5. PMID: 17255476.

Porras-Yakushi TR, Whitelegge JP, Clarke S. (2007) Yeast ribosomal/cytochrome c SET-domain methyltransferase subfamily: Identification of Rpl23ab methylation sites and recognition motifs. J Biol Chem. 282 (17), 12368-76. PMID 17327221

Waldron RT, Whitelegge JP, Faull KF, Rozengurt E. (2007) Identification of a novel phosphorylation site in c-jun directly targeted in vitro by protein kinase D. Biochem Biophys Res Commun. 356(2):361-367. PMID: 17359934

Boutz DR, Cascio D, Whitelegge J, Perry LJ, Yeates TO. (2007) Discovery of a Thermophilic Protein Complex Stabilized by Topologically Interlinked Chains. J Mol Biol. 368 (5), 1332-44. PMID: 17395198

Zabrouskov V, Whitelegge JP. (2007) Increased Coverage in the Transmembrane Domain with Activated-Ion Electron Capture Dissociation for Top-Down Fourier-Transform Mass Spectrometry of Integral Membrane Proteins. J Proteome Res. 6 (6), 2205-2210. PMID: 17441748

Watanabe J, Chou KJ, Liao JC, Miao Y, Meng HH, Ge H, Grijalva V, Hama S, Kozak K, Buga G, Whitelegge JP, Lee TD, Farias-Eisner R, Navab M, Fogelman AM, Reddy ST. (2007) Differential association of hemoglobin with pro-inflammatory high density lipoproteins in atherogenic/hyperlipidemic mice - a novel biomarker of atherosclerosis. J Biol Chem. 282(32): 23698-707. PMID: 17556366

Banci L, Bertini I, Durazo A, Girotto S, Gralla EB, Martinelli M, Valentine JS, Vieru M, Whitelegge JP. (2007) Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: A possible general mechanism for familial ALS. Proc Natl Acad Sci USA. 104(27):11263-7. PMID: 17592131

Xie J, Marusich MF, Souda P, Whitelegge J, Capaldi RA. (2007) The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11. FEBS Lett. 581(18): 3545-9. PMID: 17624330

Bortz E, Wang L, Jia Q, Wu TT, Whitelegge JP, Deng H, Zhou ZH, Sun R. 2007 Murine gammaherpesvirus 68 ORF52 encodes a tegument protein required for virion morphogenesis in the cytoplasm. J Virol. 81(18): 10137-50. PMID: 17634243

Taylor CF, Paton NW, Lilley KS, Binz PA, Julian RK Jr, Jones AR, Zhu W, Apweiler R, Aebersold R, Deutsch EW, Dunn MJ, Heck AJ, Leitner A, Macht M, Mann M, Martens L, Neubert TA, Patterson SD, Ping P, Seymour SL, Souda P, Tsugita A, Vandekerckhove J, Vondriska TM, Whitelegge JP, Wilkins MR, Xenarios I, Yates JR 3rd, Hermjakob H. (2007) The minimum information about a proteomics experiment (MIAPE). Nat Biotechnol. 25(8): 887-93.  PMID: 17687369

Whitelegge JP, Zabrouskov V, Halgand F, Souda P, Bassilian S, Yan W, Wolinsky L, Loo JA, Wong DTW, Faull KF. (2007) Protein-Sequence Polymorphisms and Post-translational Modifications in Proteins from Human Saliva using Top-Down Fourier-transform Ion Cyclotron Resonance Mass Spectrometry. International Journal Mass Spectrometry 268, 190-197. PMID: 19050733

Fujishige NA, Lum MR, De Hoff PL, Whitelegge JP, Faull KF, Hirsch AM. (2008) Rhizobium common nod genes are required for biofilm formation. Mol Microbiol. 67(3):504-15. PMID: 18086203

Shaw BF, Lelie HL, Durazo A, Nersissian AM, Xu G, Chan PK, Gralla EB, Tiwari AJ, Hayward LJ, Borchelt DR, Valentine JS, Whitelegge JP. (2008) Detergent insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxide dismutase-1. J Biol Chem. 283(13):8340-50 PMID: 18192269

Grintsevich EE,  Benchaar SA,  Warshaviak D,  Boontheung P,  Halgand F,  Whitelegge JP,  Faull KF,  Loo RR,  Sept D,  Loo JA,  Reisler E. (2008) Mapping the cofilin binding site on yeast G-actin by chemical cross-linking., J Mol Biol. 377(2):395-409. PMID: 18258262

Denny P,  Hagen FK,  Hardt M,  Liao L,  Yan W,  Arellanno M,  Bassilian S,  Bedi GS,  Boontheung P,  Cociorva D,  Delahunty CM,  Denny T,  Dunsmore J,  Faull KF,  Gilligan J,  Gonzalez-Begne M,  Halgand F,  Hall SC,  Han X,  Henson B,  Hewel J,  Hu S,  Jeffrey S,  Jiang J,  Loo JA,  Ogorzalek Loo RR,  Malamud D,  Melvin JE,  Miroshnychenko O,  Navazesh M,  Niles R,  Park SK,  Prakobphol A,  Ramachandran P,  Richert M,  Robinson S,  Sondej M,  Souda P,  Sullivan MA,  Takashima J,  Than S,  Wang J,  Whitelegge JP,  Witkowska HE,  Wolinsky L,  Xie Y,  Xu T,  Yu W,  Ytterberg J,  Wong DT,  Yates JR 3rd,  Fisher SJ., The Proteomes of Human Parotid and Submandibular/Sublingual Gland Salivas Collected as the Ductal Secretions., J Proteome Res. 2008 May 2;7(5):1994-2006.

Joh NH, Min A, Faham S, Whitelegge JP, Yang D, Woods VL, Bowie JU. (2008) Modest stabilization by most H-bonded side-chain interactions in membrane proteins. Nature 453:1266-70 PMID: 18500332

Shaw BF,  Schneider GF,  Bilgicer B,  Kaufman GK,  Neveu JM,  Lane WS,  Whitelegge JP,  Whitesides GM., Lysine acetylation can generate highly charged enzymes with increased resistance towards irreversible inactivation., Protein Sci. 2008 May 1. [Epub ahead of print], PMID: 18451358

Keire DA,  Whitelegge JP,  Bassilian S,  Faull KF,  Wiggins BW,  Mehdizadeh OB,  Reidelberger RD,  Haver AC,  Sayegh AI,  Reeve JR Jr. (2008) A new endogenous form of PYY isolated from canine ileum: Gly-extended PYY(1-36)., Regul Pept. 151(1-3):61-70. PMID: 18501442

Lu H,  Zong C,  Wang Y,  Young GW,  Deng N,  Souda P,  Li X,  Whitelegge J,  Drews O,  Yang PY,  Ping P. (2008) Revealing the dynamics of 20S proteasome phosphoproteome: A combined CID and ETD approach. Mol Cell Proteomics 7(11):2073-89. PMID: 18579562

Budzik JM,  Marraffini LA,  Souda P,  Whitelegge JP,  Faull KF,  Schneewind O. (2008) Amide bonds assemble pili on the surface of bacilli., Proc Natl Acad Sci USA. 105(29):10215-20. PMID: 18621716

Webb KJ,  Laganowsky A,  Whitelegge JP,  Clarke SG.,Identification of Two SET Domain Proteins Required for Methylation of Lysine Residues in Yeast Ribosomal Protein Rpl42ab., J Biol Chem. 2008 Dec 19;283(51):35561-8.  PMID: 18957409

Chattopadhyay M,  Durazo A,  Sohn SH,  Strong CD,  Gralla EB,  Whitelegge JP,  Valentine JS. (2008) Initiation and elongation in fibrillation of ALS-linked superoxide dismutase., Proc Natl Acad Sci USA. 105(48):18663-8. PMID: 19022905

Prudencio M, Durazo A, Whitelegge JP, Borchelt DR., Modulation of mutant superoxide dismutase 1 aggregation by co-expression of wild-type enzyme., J Neurochem. 2008 Dec 11. [Epub ahead of print], PMID: 19077113

Erales J, Gontero B, Whitelegge J, Halgand F., Mapping of a copper binding site on the small CP12 chloroplastic protein, using top down mass spectrometry and site- directed mutageneses., Biochem J. 2008 Dec 22. [Epub ahead of print], PMID: 19099541

Doolittle MH,  Ben-Zeev O,  Bassilian S,  Whitelegge JP,  Péterfy M,  Wong H.  Hepatic lipase maturation:A partial proteome of interacting factors., , J Lipid Res. 2009 Jan 8. [Epub ahead of print]

B. Research Papers  (Peer reviewed, in Press)

Puppione, D.L., Bassilian, S., Souda, P., MacDonald M.H., Halgand, F., Whitelegge, J.P. (2008) Mass spectral analysis of the apolipoproteins on dog (Canis lupis familiaris) high density lipoproteins. Detection of Apolipoprotein A-II. Comp. Biochem. Physiol. D, in press