Professor Julian Whitelegge
- Bottom-up proteomics in various diseases and systems
- Membrane protein structure and function
- Top-down proteomics of membrane and other proteins
- Proteomics in diabetes research
- Biomarkers of radiation exposure
- Proteomic biomarker investigations in breast cancer
- Protein misfolding and neurodegenerative disease
- Mechanisms of SOD1-linked amyotrophic lateral sclerosis
- Microfluidics for high-throughput hydrogen-deuterium exchange of proteins
- Pharmacokinetics of new potential drugs
Laboratory Projects
- Glutathione turnover in various diseases and systems
- The role of sulfated lipids in egg fertilization
- Protein misfolding in pancreatitis and alcohol abuse
- Metabolomic profiling in traumatic brain injury
- Biomarker investigations in:
- Kidney rejection
- Prostate cancer
- Alzheimer’s disease
- The role of de novo and salvage DNA synthesis in cancer
- Organic residue analysis in ancient archeological samples
- The translational accuracy in microbial protein biosynthesis
- Glutathionylation of a Yersinia pestis protein
- Lipid profiling in atherosclerosis and other diseases
- Pharmacokinetics of new potential drugs