The UCLA Pasarow Mass Spectrometry Laboratory consists of an intellectually vibrant group of individuals who share a common commitment to the advancement of science and the training of students through innovative research and educational endeavors.

NSF and NIH Shared Instrument Grants over the past few years have led to the acquisition of several new pieces of equipment that complete the suite of available instrumentation. The availability of gas and liquid chromatography and electron impact (EI), chemical (CI), electrospray (ESI), and laser desorption (LD) ionization methods together in one facility is a feature of this Laboratory that is vital for the wide variety of chemical and biochemical research conducted at UCLA.

In essence, we use a range of mass spectrometric techniques to characterize the structure and abundances of various molecules including proteins, small molecules, and lipids. To get a feeling for how mass spectrometry actually works, see the video below showing the physical manipulation of charged particles (Lycopodium spores) using an Electrodynamic Ion Trap designed by Newtonian Labs.

Metabolomic and Proteomic Analyses